hrp0084p3-730 | Diabetes | ESPE2015

β-Cells’ Functional Exhaustion at Type 1 Diabetes Onset may Lead to Early Microvascular Complications

Papadopoulou Nektaria , Dacou-Voutetakis Catherine , Chrousos George , Kanaka-Gantenbein Christina

Background: Diabetic ketoacidosis (DKA) is a severe and often the inaugural clinical manifestation of type 1 Diabetes (T1D). Diabetic nephropathy is one of the most devastating chronic complications of T1D and itsÂ’ early diagnosis is traditionally based on microalbuminuria.Objective and hypotheses: The aim was to investigate the possible associations between the initial clinical manifestations and the chronic complications of T1D.<p class="abste...